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Understanding nanoscale phenomena using single particle mass spectrometry and improvement of its performance - a review.
Lee D; Lee K-S; Cho S-W; Zhou L; Miller A; Park K; Zachariah MR
Chem Phys Res J 2008 Jan; 2(1-2):61-96
Single particle mass spectrometry (SPMS), that is capable of sizing and chemically analyzing single nanoparticle, has offered an opportunity for better understandings of mechanisms of aerosol-based nanoparticle synthesis, origin of environmental aerosol particles, and combustion of energetic nanoparticles. Also as ultrafine and accumulation-mode aerosols in the size range of 30 - 300nm can penetrate deeply into human lung and cause serious diseases, the needs of advanced SPMS has been rapidly growing. In this article, we therefore offer a broad review for single particle mass spectrometry, from its working principle and several concerns for interpretation of the data, to the applications to probe the nanoscale phenomena, based on our previous publications on the SPMS. Also this article is written to describe how to develop and improve the SPMS for better quantification of data and more efficient detection, so as to provide a simple designing guideline to SPMS developers.
Nanotechnology; Analytical-processes; Particulates; Mass-spectrometry; Performance-capability; Nanoparticles; Particle sizers; Particle size analysis; Chemical analysis; Aerosols; Aerosol particles; Health effects; Quantitative analysis; Chemical synthesis; Nanoscale; Author Keywords: Single Particle Mass Spectrometry; Nano-scale Phenomena; Aerosol; Health Effect; Quantification; Efficient Detection
Donggeun Lee, School of Mechanical Engineering, Pusan Clean Coal Center, Pusan National University, 30 Jangjeon, Geumjeong, Busan 609-735, Korea
Issue of Publication
Chemical Physics Research Journal
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division