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Understanding nanoscale phenomena using single particle mass spectrometry and improvement of its performance - a review.

Authors
Lee D; Lee K-S; Cho S-W; Zhou L; Miller A; Park K; Zachariah MR
Source
Chem Phys Res J 2008 Jan; 2(1-2):61-96
NIOSHTIC No.
20034507
Abstract
Single particle mass spectrometry (SPMS), that is capable of sizing and chemically analyzing single nanoparticle, has offered an opportunity for better understandings of mechanisms of aerosol-based nanoparticle synthesis, origin of environmental aerosol particles, and combustion of energetic nanoparticles. Also as ultrafine and accumulation-mode aerosols in the size range of 30 - 300nm can penetrate deeply into human lung and cause serious diseases, the needs of advanced SPMS has been rapidly growing. In this article, we therefore offer a broad review for single particle mass spectrometry, from its working principle and several concerns for interpretation of the data, to the applications to probe the nanoscale phenomena, based on our previous publications on the SPMS. Also this article is written to describe how to develop and improve the SPMS for better quantification of data and more efficient detection, so as to provide a simple designing guideline to SPMS developers.
Keywords
Nanotechnology; Analytical-processes; Particulates; Mass-spectrometry; Performance-capability; Nanoparticles; Particle sizers; Particle size analysis; Chemical analysis; Aerosols; Aerosol particles; Health effects; Quantitative analysis; Chemical synthesis; Nanoscale; Author Keywords:; Detectors; Author Keywords: Single Particle Mass Spectrometry; Nano-scale Phenomena; Aerosol; Health Effect; Quantification; Efficient Detection
Contact
Donggeun Lee, School of Mechanical Engineering, Pusan Clean Coal Center, Pusan National University, 30 Jangjeon, Geumjeong, Busan 609-735, Korea
Publication Date
20080101
Document Type
Journal Article
Email Address
donglee@pusan.ac.kr
Fiscal Year
2008
NTIS Accession No.
NTIS Price
Issue of Publication
1-2
ISSN
1935-2492
NIOSH Division
SRL
Priority Area
Mining
Source Name
Chemical Physics Research Journal
State
MD; WA
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