The Division of Physical Sciences and Engineering (DPSE) of NIOSH had for many years a written Safety Manual. With the promulgation of OSHA standard 1910.1450, DPSE replaced the Safety Manual with a CHP in 1991; and revised it in 1995. Chemical, biological and ventilation engineering research are conducted. General chemical research is conducted in the High Hazard Laboratory. Neat and concentrated carcinogens, dilute chemical agents and biological organisms are handled in the High Containment Laboratory. NIOSH scientists frequently conduct work site evaluations which include: office buildings, manufacturing plants, residences, road repair, foundries, mines, and hospitals. The CHP addresses chemical and biological organism inventories, hazard communication, evacuation, medical monitoring, project plan development, shop practices, chemical safety, biosafety, field studies and respirator fit testing. The CHP is the result of employee involvement and management's concern for employee and community health.