NIOSHTIC-2 Publications Search

Architecture and cellular composition of the air-blood barrier.

Pinkerton KE; Gehr P; Crapo JD

Treatise on Pulmonary Toxicology. Comparative Biology of the Normal Lung. Boca Raton. FL: CRC Press, 1992 Feb; 1:121-128

20033783

There are over 4000 different varieties of mammals. Among the terrestrial mammals, body size ranges from the 2-g shrew to the 6600-kg elephant. Lung tissue mass involved in gas exchange in this class of animal , also covers a wide spectrum. Differences in the dimensions of the mammalian respiratory system are intriguing, since those pulmonary tissues involved in gas exchange are strikingly similar in organization and cellular composition, yet serve vastly different oxygen consumption needs in a highly efficient manner for animals spanning more than a three million-fold difference in total body mass (Gehr et aI., 1981). The purpose of this chapter is to review and to compare the anatomy and cellular composition of the alveolar region in mammalian lungs.

Respiratory-function-tests; Respiratory-gas-analysis; Respiratory-hypersensitivity; Respiratory-irritants; Respiratory-rate; Respiratory-system-disorders; Animal-studies; Animals; Cellular-function; Cellular-reactions; Cellular-respiration; Cellular-structures; Lung-burden; Lung-cells; Lung-disorders; Lung-function; Lung-irritants; Alveolar-cells; Airborne-dusts; Airborne-fibers

K. E. Pinkerton, Department of Anatomy School of Veterinary Medicine University of California, Davis, CA 95616-8542

19920201

Chapter

1055222

Cooperative Agreement

1992

9780849388392

Cooperative-Agreement-Number-U07-CCU-906162

Treatise on Pulmonary Toxicology. Comparative Biology of the Normal Lung

CA; NC

University of California - Davis