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Methyl jasmonate enhances antioxidant activity and flavonoid content in blackberries (Rubus sp.) and promotes antiproliferation of human cancer cells.
Wang-SY; Bowman-L; Ding-M
Food Chem 2008 Jan; 107(3):1261-1269
The effects of preharvest methyl jasmonate (MJ) application on fruit quality, antioxidant activity and flavonoid content in blackberries (Rubus sp.) were determined. Anticancer activity against human lung A549 cells and HL-60 leukemia cells was also evaluated. Three blackberry cultivars (Chester Thornless, Hull Thornless and Triple Crown) were used in these experiments. Blackberries treated with MJ (0.01 and 0.1 mM) had higher soluble solids content, and lower titratable acids than untreated fruit as well as enhanced content of flavonoids and increased antioxidant capacity. Extracts of treated fruit showed enhanced inhibition of A549 cell and HL-60 cell proliferation and induced the apoptosis of HL-60 cells. Cultivar Hull Thornless had higher soluble solids and lower titratable acids compared to cv. Chester Thornless and Triple Crown. On the basis of fresh weight of fruit, Hull Thornless also had significantly higher anthocyanin, total phenolic content, antioxidant and antiproliferation activity than other two cultivars.
Agricultural-chemicals; Agricultural-industry; Agricultural-processes; Agriculture; Antifungals; Lung; Lung-cells; Leukocytes; Cell-biology; Cell-function; Cell-morphology; Cellular-reactions; Fungicides
Shiow Y. Wang, Genetic Improvement of Fruit and Vegetable Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705-2350
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Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division