Issues when modeling benzene, toluene, and xylene exposures using a literature database.
Hein-MJ; Waters-MA; van Wijngaarden-E; Deddens-JA; Stewart-PA
J Occup Environ Hyg 2008 Jan; 5(1):36-47
A database of benzene, toluene, and xylene measurements was compiled from an extensive literature review that contained information on several exposure determinants, including job type, operation, mechanism of release, process type, ventilation, temperature, distance from the source, quantity, and location. The database was used to develop statistical models for benzene, toluene, and xylene exposure as a function of operation and other workplace determinants. These models can be used to predict exposure levels for subjects enrolled in community-based case-control studies. This article presents the derived parameter estimates for specific operations and additional workplace exposure determinants and describes a number of statistical and data limitation issues that are inherent in determinants modeling of historical published data.
Solvents; Solvent-vapors; Models; Computer-models; Statistical-analysis; Exposure-assessment; Exposure-levels; Case-studies
Misty J. Hein, Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Parkway, Mail-Stop R-13, Cincinnati, OH 45226
71-43-2; 108-88-3; 1330-20-7
Agriculture, Forestry and Fishing
Journal of Occupational and Environmental Hygiene