Molecular and cellular biomarker responses to pesticide exposure in juvenile chinook salmon (Oncorhynchus tshawytscha).
Authors
Eder-KJ; Leutenegger-CM; Wilson-BW; Werne-I
Source
Mar Environ Res 2004 Aug-Dec; 58(2-5):809-813
Abstract
We determined the effects of two pesticides, chlorpyrifos and esfenvalerate in juvenile Chinook salmon. Four to five month old salmon were exposed to a range of pesticide concentrations, and tissue samples of surviving fish were analyzed for stress protein expression, cytokine transcription, and acetylcholinesterase (AChE) activity. At the highest concentrations, both pesticides led to complete mortality, whereas medium and low concentrations resulted in high survival rates. Significant differences in stress protein expression, cytokine transcription and AChE activity were found between control and surviving chlorpyrifos-exposed fish. Elevated stress protein expression was the only detectable response to esfenvalerate.
Keywords
Pesticides; Chemical-analysis; Sea-water; Cytotoxic-effects; Cytotoxicity; Cytotoxins; Proteins; Protein-biochemistry
CAS No.
2921-88-2; 66230-04-4
Document Type
Journal Article
Email Address
kjeder@ucdavis.edu
Funding Type
Agriculture; Cooperative Agreement
Identifying No.
Cooperative-Agreement-Number-U50-OH-007550
Source Name
Marine Environmental Research
Performing Organization
University of California - Davis
