Dust generator for inhalation studies with limited amounts of archived particulate matter.
Teague-SV; Veranth-JM; Aust-AE; Pinkerton-KE
Aerosol Sci Tech 2005 Feb; 39(2):85-91
A novel design for a dry-aerosol generator that efficiently produces a well-dispersed dust suspension using small quantities of a PM2.5-enriched powder sample is described. The motivation to develop a highly efficient dry-aerosol particle generator was to facilitate collaborative projects that combine in vitro cell culture experiments and multiday inhalation exposures using a single batch of well-characterized particles. Premixing of the test particles with larger diameter glass beads permits delivery of aerosol concentrations from 100-1000 g/m3 to an exposure chamber using only milligram quantities of the test powder per hour. Examination of exposure chamber filter samples by scanning electron microscopy showed well-dispersed particles of the test powder free of glass spheres or fragments. Data are presented from experiments using coal fly ash as the test powder to illustrate the system performance.
Dust-exposure; Dust-inhalation; Dust-measurement; Dust-counting; Dust-collectors; Aerosol-particles; Aerosols; Electron-absorption-spectrometry; Microscopic-analysis; Aerosol-generators
Stephen V. Teague: University of California Davis, Davis, California, USA
Work Environment and Workforce: Special Populations
Aerosol Science and Technology
University of California, Davis, California