NIOSHTIC-2 Publications Search

Pulmonary effects of single-walled carbon nanotubes: inflammatory response, oxidative stress/signaling, and recognition by macrophages.

Kagan-VE; Rao-KMK; Kisin-ER; Young-S-H; Meighan-T; Murray-AR; Tyurina-YY; Castranova-V; Shvedova-AA

Nanotechnology - toxicological issues and environmental safety (NATO science for peace and security series / NATO science for peace and security series C: environmental security). Simeonova PP, Opopol N, Luster MI. eds. Dordrecht, The Netherlands: Springer, 2007 May; :65-75

http://dx.doi.org/10.1007/978-1-4020-6076-2_4

20032331

Nanosized materiaols and nano-scaled processes are believed to be beneficial for many industries as well as for medicine. However, irrational unjustified use of nanomaterials may also pose risks to human health and the environment, particularly single-walled carbon nanotubes, such as their decytotoxid effects, their ability to cause an inflammatory response, and induction of oxidative stress. Further, recognigion and engulfment of nanotubes in tissue and circulation are discussed. Possible involvement of lung fibroblast pulmonary responses to nanotubes are considered.

Aerosols; Aerosol-particles; Airborne-particles; Airborne-fibers; Toxicology; Nanotechnology; Author Keywords: occupational exposure; free radicals; lung fibrosis; neutrophils; transition metals

Pathology/Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505

20070515

Conference/Symposia Proceedings

Simeonova-PP; Opopol-N; Luster-MI

Grant

2007

9781402060755

Grant-Number-R01-OH-008282

HELD

Manufacturing

Nanotechnology - toxicological issues and environmental safety (NATO science for peace and security series / NATO science for peace and security series C: environmental security)

WV; PA

University of Pittsburgh at Pittsburgh