Chronic bronchitis among nonsmoking farm women in the Agricultural Health Study.
Valcin M; Henneberger PK; Kullman GJ; Umbach DM; London SJ; Alavanja MCR; Sandler DP; Hoppin JA
J Occup Environ Med 2007 May; 49(5):574-583
Objective: The purpose of this study was to examine agricultural risk factors for chronic bronchitis among nonsmoking farm women. Methods: We used self-reported enrollment data from the 21,541 nonsmoking women in the Agricultural Health Study to evaluate occupational risk factors for prevalent chronic bronchitis among farm women. Odds ratios (ORs) for chronic bronchitis for occupational exposures were adjusted for age, state, and related agricultural exposures. Results: Applying manure and driving combines were independently associated with chronic bronchitis. Off-farm job exposures associated with chronic bronchitis were organic dusts, asbestos, gasoline, and solvents. Five pesticides were associated with chronic bronchitis after multivariate adjustment and sensitivity analyses: dichlorvos (OR=1.63, 95% CI=1.01, 2.61), DDT (OR=1.67, 95% CI=1.13, 2.47), cyanazine (OR=1.88, 95% CI=1.00, 3.54), paraquat (OR=1.91, 95% CI=1.02, 3.55), and methyl bromide (OR=1.82, 95% CI=1.02, 3.24). Conclusion: Pesticides as well as grain and dust exposures were associated with chronic bronchitis among nonsmoking farm women.
Worker-health; Occupational-health; Risk-factors; Risk-analysis; Agricultural-workers; Agriculture; Pulmonary-function; Pulmonary-system-disorders; Pesticides-and-agricultural-chemicals; Farmers; Breathing-atmospheres; Breathing; Women
Jane Hoppin, NIEHS, Epidemiology Branch, MD A3-05, PO Box 12233, Research Triangle Park, NC 27709-2233
62-73-7; 21725-46-2; 1910-42-5; 74-83-9
Journal of Occupational and Environmental Medicine