Permeation of a malathion formulation through butyl gloves.
Lin-YW; Que Hee-SS
J Hazard Mater 1998 Jun; 60(2):143-158
The factors that determined the permeation kinetics of a commercial malathion formulation (Prent) and its reconstituted cocktail of malathion and its xylene-range fraction inert ingredients at Prent concentrations (Recon) were investigated for an unlined unsupported butyl industrial type glove in an ASTM-type permeation cell with liquid 2-propanol collection and subsequent analysis by gas chromatography/mass spectrometry. For both Prent and Recon, the steady-state permeation rate Ps correlated inversely with the logarithm of the breakthrough time tb1, as did logPs with logtb- Ps1 logPs1 Ps/tl and logPs/tl (where tl is the lag time) versus the logarithm of the weight percentage of component divided by the total weight were linear too. After accounting for mixture composition, the second strongest linear regression term was liquid molar volume, and the strongest third term was octanol-water partition coefficient (logKow). Retention volumes, l/R(tl) at tl and l/R(ts1) at the first observed time in the steady-state ts1 of each chemical in Prent and Recon, were also similarly correlated to the weight percentage and logKow or Snyder elution strength (Eo). At least three independent variables are necessary to account for the permeation of this complex mixture. One factor accounts for composition, another for molecular size, and the third for partitioning behavior.
Gloves; Pesticide-residues; Pesticide-industry; Insecticides; Sulfur-compounds; Alcohols; Gas-chromatography; Protective-clothing
Department of Environmental Health Sciences and UCLA Center for Occupational and Environmental Health, UCLA School of Public Health, 10833 Le Conte Avenue, Los Angeles, CA 90095-1772, USA
Research Tools and Approaches: Intervention Effectiveness Research
Journal of Hazardous Materials
University of California, School of Public Health, Department of Environmental Health Sciences, Los Angeles, California