Use of solid-phase microextraction to detect and quantify gas-phase dicarbonyls in indoor environments.
Pacolay-BD; Ham-JE; Wells-JR
J Chromatogr A 2006 Oct; 1131(1-2):275-280
Solid-phase microextraction (SPME) was evaluated for the detection and quantification of the gas-phase dicarbonyls, glyoxal (GLY) and methylglyoxal (MGLY). Additionally, polydimethylsiloxane (PDMS), polydimethylsiloxane/divinylbenzene (PDMS/DVB), and carbowax/divinylbenzene (CW/DVB) fibers were tested to determine the optimum fiber for detection of these species. GLY and MGLY were derivatized with O-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine hydrochloride (PFBHA), extracted with SPME from headspace or bag chamber and then analyzed by GC/MS. The PDMS/DVB SPME fiber for on-fiber derivatization and subsequent sampling for gas-phase methylglyoxal provided the optimum combination of analytical reproducibility and sensitivity. Linearity of the calibration curve was achieved across a range of 11-222mug/m(3) (4-75ppb).
Chromatographic-analysis; Analytical-processes; Analytical-chemistry; Indoor-air-pollution; Indoor-environmental-quality
Exposure Assessment Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
Research Tools and Approaches: Exposure Assessment Methods
Journal of Chromatography A