Airway responses in healthy and asthmatic subjects following exposure to low ambient air temperature.
Zuskin-E; Schachter-EN; Mustajbegovic-J
Acta Med Croatica 1996 Jan; 50(2):97-101
Ventilatory capacity following exposure to low ambient air temperature (-5 degrees C) was measured in 46 male and 37 female medical students. In healthy subjects there was an increase in all test parameters during a four-hour exposure as compared to preexposure values. However, six students with bronchial asthma showed a decrease in ventilatory capacity tests following exposure to low temperature. The changes in healthy subjects as well as in asthmatics were most pronounced for the maximal flow rates at 50% and the last 25% of the vital capacity (FEF50, FEF25). The mean increase in FEF25 for healthy subjects was recorded up to a +15.1% and +6.4% increase in nonsmokers and smokers, respectively. In asthmatics, the largest decrease of FEF25 was -21.5%. Authors' data indicated that environmental exposure to low ambient air temperature caused an increase of ventilatory function tests in healthy subjects and a decrease in asthmatics, particularly in flow rates at lower lung volumes.
Bronchial-asthma; Diseases; Temperature-effects; Exposure-assessment; Air-temperature; Exposure-levels; Smoking
Acta Medica Croatica
Mount Sinai School of Medicine, New York, New York