Effects of repeated vibration exposures in muscle tissue.
Wirth-O; Waugh-S; Johnson-C; Miller-GR; Krajnak-KM
Proceedings of the First American Conference on Human Vibration, June 5-7, 2006, Morgantown, West Virginia. Dong R, Krajnak K, Wirth O, Wu J, eds., Morgantown, WV: National Institute for Occupational Safety and Health, 2006 Jun; :156-157
Workers exposed to vibrating hand tools are at risk of developing symptoms such as cold-induced vasospasms, loss of tactile sensitivity, and loss of grip strength in the fingers and hands. These symptoms are known collectively as vibration white finger (VWF) or hand-arm vibration syndrome (HAVS). Symptoms of VWF or HAVS are in part due to repeated and prolonged peripheral vasoconstriction. The reduction in blood flow that occurs with vasoconstriction can result in oxygen deprivation (hypoxia) in soft tissues, such as nerves and muscle, and lead to functional and structural changes in these tissues. The present study examined muscle tissue to determine if vibration-induced changes in transcript levels and protein concentrations result in enhanced vasoconstriction and hypoxia. Manual dexterity was also assessed intermittently to determine if vibration-induced changes in cellular factors are accompanied by performance deficits.
Vibration-exposure; Vibration; Power-tools; Ergonomics; Hand-tools; Vibration-disease; Vibration-effects; Neurovascular-disorders
Dong-R; Krajnak-K; Wirth-O; Wu-J
Disease and Injury: Musculoskeletal Disorders of the Upper Extremities
Proceedings of the First American Conference on Human Vibration, June 5-7, 2006