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Effects of repeated vibration exposures in muscle tissue.

Wirth O; Waugh S; Johnson C; Miller GR; Krajnak KM
Proceedings of the first American conference on human vibration, June 5-7, 2006, Morgantown, West Virginia. Dong R, Krajnak K, Wirth O, Wu J, eds. Morgantown: WV: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2006-140, 2006 Jun; :156-157
Workers exposed to vibrating hand tools are at risk of developing symptoms such as cold-induced vasospasms, loss of tactile sensitivity, and loss of grip strength in the fingers and hands. These symptoms are known collectively as vibration white finger (VWF) or hand-arm vibration syndrome (HAVS). Symptoms of VWF or HAVS are in part due to repeated and prolonged peripheral vasoconstriction. The reduction in blood flow that occurs with vasoconstriction can result in oxygen deprivation (hypoxia) in soft tissues, such as nerves and muscle, and lead to functional and structural changes in these tissues. The present study examined muscle tissue to determine if vibration-induced changes in transcript levels and protein concentrations result in enhanced vasoconstriction and hypoxia. Manual dexterity was also assessed intermittently to determine if vibration-induced changes in cellular factors are accompanied by performance deficits.
Vibration-exposure; Vibration; Power-tools; Ergonomics; Hand-tools; Vibration-disease; Vibration-effects; Neurovascular-disorders
Publication Date
Document Type
Conference/Symposia Proceedings
Dong R; Krajnak K; Wirth O; Wu J
Fiscal Year
NTIS Accession No.
NTIS Price
NIOSH Division
Priority Area
Disease and Injury: Musculoskeletal Disorders of the Upper Extremities
Source Name
Proceedings of the first American conference on human vibration, June 5-7, 2006, Morgantown, West Virginia