An estimate of prostate cancer prevalence for a demographically similar workforce population.
Westra CS; Ducatman AM; Niewiadonska-Bugaj M; Hobbs GR
WV Med J 1999 May-Jun; 95(3):116-122
To obtain an estimate of prostate cancer prevalence when screening is applied to a workforce, we conducted a search of the English world literature from West Virginia University. Thirty-one papers which met selection criteria for screening were followed by histopathologic diagnosis. Publications using Prostate Specific Antigen (PSA) as a screening test were reviewed. The data from these papers were combined. Population characteristics were then selected to represent the demographics of a working population. Prostate cancer prevalence estimates for the demographics of a working population were calculated using a weighted mean after relevant studies lacked homogeneity and therefore failed meta-analysis. The expected prevalence of prostate cancer in a workplace surveillance population is 2.03% (95% C.I. from 1.69% to 2.37%). This information is useful to entities considering workplace surveillance. Selection bias, geographic location, and uncertainty in prediction of a representative workforce population may strongly influence estimates.
Occupational-health-services; Cancer; Prostate-cancer; Histopathology; Workers; Worker-health; Demographic-characteristics; Surveillance-programs
West Virginia Medical Journal
West Virginia University, School of Medicine, Institute of Occupational and Environmental Health, Morgantown, West Virginia