Pesticide exposure, host susceptibility factors and risk of Parkinson's disease: an introduction to a work in progress.
Greenlee-AR; Burmester-JK; Hiner-BC
WMJ 2002 Jan; 101(5):20-24
Linking exposures with biomarker data may provide a clearer understanding of the mechanisms by which agrochemical exposures influence the occurrence of PD and may assist with formulating strategies for reducing adverse health consequences for agricultural and other workers by policy design, education, and research. It may well be that the Parkinson phenotype is not the result of a single gene defect or of exposure to a single environmental toxin, but rather multiple potential combinations of genetic and environmental interactions. Ultimately the hope is that knowledge gained in studies such as this will allow clinicians to screen individuals for susceptibility genes, and advise them on specific environmental factors that need to be avoided in order to prevent the subsequent development of PD years later.
Cell-biology; Cell-function; Cell-metabolism; Cell-morphology; Cellular-function; Cellular-structures; Pest-control; Pesticide-industry; Pesticide-residues; Pesticides; Pesticides-and-agricultural-chemicals
Marshfield Medical Research Foundation, 1000 N Oak Ave, Marshfield, WI 54449
Wisconsin Medical Journal
Marshfield Clinic Research Foundation