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Parental exposure to organic solvents and reduced birth weight.
Ha E; Cho SI; Chen D; Chen C; Ryan L; Smith TJ; Xu X; Christiani DC
Arch Environ Health 2002 May; 57(3):207-214
The authors investigated the association of birth weight with maternal and paternal exposure to organic solvents in 1,222 couples employed in a large petrochemical corporation in Beijing, China, during the period between 1994 and 1998. A trained interviewer assessed parental exposures to organic solvents. The authors used generalized additive models to examine the association between birth weight and parental exposure to organic solvents. After the authors adjusted for potential confounders, maternal exposure to solvents was significantly associated with reduced birth weight (-81.7 gm, 95% confidence interval = -106.3, -3.1), and reduced birth weights of female babies and of younger mothers' babies were statistically significant. Maternal exposure to organic solvents was associated with reduced birth weight in this population, but paternal exposure to organic solvents was not similarly associated.
Reproductive system disorders; Reproductive hazards; Pregnancy; Organic solvents; Occupational exposure; Risk factors; Statistical analysis; Epidemiology
Eunhee Ha, M.D., Ph.D., Department of Preventive Medicine, Ewha Woman's University College of Medicine, 911-1 Mok-6-Dong Yangchun-Gu, Seoul, South Korea
71-43-2; 8006-61-9; 7439-96-5; 7783-06-4; 7664-41-7
Issue of Publication
Disease and Injury: Fertility and Pregnancy Abnormalities
Archives of Environmental Health
Harvard University, Boston, Massachusetts
Page last reviewed: April 9, 2021
Content source: National Institute for Occupational Safety and Health Education and Information Division