NIOSHTIC-2 Publications Search

Parental exposure to organic solvents and reduced birth weight.

Ha-E; Cho-SI; Chen-D; Chen-C; Ryan-L; Smith-TJ; Xu-X; Christiani-DC

Arch Environ Health 2002 May; 57(3):207-214

http://dx.doi.org/10.1080/00039890209602938

20029505

The authors investigated the association of birth weight with maternal and paternal exposure to organic solvents in 1,222 couples employed in a large petrochemical corporation in Beijing, China, during the period between 1994 and 1998. A trained interviewer assessed parental exposures to organic solvents. The authors used generalized additive models to examine the association between birth weight and parental exposure to organic solvents. After the authors adjusted for potential confounders, maternal exposure to solvents was significantly associated with reduced birth weight (-81.7 gm, 95% confidence interval = -106.3, -3.1), and reduced birth weights of female babies and of younger mothers' babies were statistically significant. Maternal exposure to organic solvents was associated with reduced birth weight in this population, but paternal exposure to organic solvents was not similarly associated.

Reproductive-system-disorders; Reproductive-hazards; Pregnancy; Organic-solvents; Occupational-exposure; Risk-factors; Statistical-analysis; Epidemiology

Eunhee Ha, M.D., Ph.D., Department of Preventive Medicine, Ewha Woman's University College of Medicine, 911-1 Mok-6-Dong Yangchun-Gu, Seoul, South Korea

AEHLAU

71-43-2; 8006-61-9; 7439-96-5; 7783-06-4; 7664-41-7

20020501

Journal Article

eunheeha@mm.ewha.ac.kr

1168572

Grant

2002

Grant-Number-R01-OH-003027

3

0003-9896

Disease and Injury: Fertility and Pregnancy Abnormalities

Archives of Environmental Health

MA

Harvard University, Boston, Massachusetts