Idiopathic pulmonary fibrosis mortality in the United States: is there any evidence of occupational risk?
Pinheiro-G; Antão-V; Wood-J; Bang-KM; Attfield-M
Eur Respir J 2005 Sep; 26(Suppl 49):S702-S703
Metal and wood dust exposure may be occupational risk factors for idiopathic pulmonary fibrosis (IPF) (Hubbard R. Eur Respir J 2001:18:119s-121s). To investigate mortality due to IPF and by specific employment (by industry). We analyzed mortality data from the National Center for Health Statistics (all deaths of U.S. residents >15 years old listed on the Record Axis) using ICD-10 cod J84.1 - "Other interstitial pulmonary diseases with fibrosis" (Diffuse pulmonary fibrosis, cryptogenic fibrosing alveolitis, Hamman-Rich syndrome, idiopathic pulmonary fibrosis). We derived age-standardized mortality rates (per million population per year) for 1999 and 2000 and proportionate mortality ratios (PMRs) for 1999, the most recent year for which 3-digit standardized industry codes were available. The annual mortality rate for IPF was 72.46 (15,472 deaths) in 1999 and 74.81 (16,303 deaths) in 2000. The five top industries with significantly elevated PMRs are shown below. Exposure to metal and wood dust is likely to occur in three of the industries with the elevated PMRs, providing further evidence that these exposures may be risk factors for IPF.
Fibrosis; Pulmonary-system-disorders; Occupational-exposure; Wood-dusts; Metals; Mortality-rates; Mortality-data; Risk-factors; Risk-analysis; Occupational-health; Occupational-hazards; Respiratory-system-disorders; Surveillance
Abstract; Conference/Symposia Proceedings
European Respiratory Journal