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Development of colorimetric indicators: a new technique to determine acid, base, and aldehyde contaminations.

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Occupational and Environmental Exposures of Skin to Chemicals, Stockholm, Sweden, June 12 -15, 2005. Morgantown, WV: National Institute for Occupational Safety and Health, 2005 Jun; :1
The objective of the study was to develop new colorimetric indicator pads for detecting acid, base, and aldehyde permeation through chemical protective gloves. Each indicator pad carries a reagent, which responds to the appropriate chemical contaminant by producing a color change. Acid, base, and aldehyde indicators were synthesized and indicator pads were designed and fabricated. Assessment of the stain sensitivity and stability of each indicator was determined using the modified ASTM F-739 and/or direct spiking of appropriate chemicals on the indicator pads. Interference testing was also performed by spiking test chemicals on the indicator pads The indicator pads were used to detect the appropriate chemical group permeating through the glove materials using the Thermo-Hand method. The Thermo-Hand method was developed to evaluate indicator pads for chemical permeation through protective gloves under simulated in-use conditions. Breakthrough times for commonly used chemical protective glove materials were determined. Quantification was performed for test chemicals by gas chromatography following solvent desorption. Some example laboratory results of this research will be described. The newly developed pads have been used for laboratory testing only and are not commercially available. However, with further development and field studies, the indicator pads could find utility in detecting, collecting, and quantitatively analyzing chemical permeation in both the liquid and vapor phases.
Risk-analysis; Protective-clothing; Protective-materials; Protective-measures; Protective-equipment; Chemical-indicators; Chemical-analysis; Analytical-chemistry; Chromatographic-analysis
Publication Date
Document Type
Fiscal Year
NIOSH Division
Priority Area
Disease and Injury: Allergic and Irritant Dermatitis
Source Name
Occupational and Environmental Exposures of Skin to Chemicals, Stockholm, Sweden, June 12 -15, 2005
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division