Incidence of asthma attributable to occupation among HMO members.
Sama-SR; Hunt-PR; Fuhlbrigge-A; Rosiello-RA; Cirillo-PA; Herrick-R
Am J Respir Crit Care Med 2004 Apr; 169(7)(Abstracts):A648
To estimate the proportion of asthma caused by workplace exposures, we identified adult-onset asthma in a New England HMO population using searches of computerized billing and claims data for March 2000 though February 2002. Of 2117 potential cases, we confirmed 906 cases after detailed review of medical records. We were able to contact and interview by telephone 405 (44.7%) of the confirmed cases. The questionnaire was designed to categorize evidence of work-related asthma for each case based on our evaluation of their reported work-related symptoms and expert ratings of their workplace exposures. Combining cases with moderate and strong evidence (n=114) for work related asthma and those with occupational RADS (n=2) to estimate the proportion of asthma attributable to occupational exposure resulted in an estimate that 28.6% (95% confidence 24.2 to 33.0%) of adult-onset asthma is work-related. This result is higher than the proportion estimated in our pilot study (21 % 95% confidence 12-32%) but within the range of estimates compatible with that much smaller study.
Epidemiology; Statistical-analysis; Humans; Pulmonary-system-disorders; Pulmonary-disorders; Respiratory-system-disorders
Susan R. Sama, ScD, Harvard School of Public Health, Exposure, Epidemiology and Risk Program, 401 Park Drive, Box 15677, Landmark Center West, Room 428, Boston, MA 21286
Abstract; Conference/Symposia Proceedings
Cooperative Agreement; Grant
American Journal of Respiratory and Critical Care Medicine
Harvard School of Public Health, Boston, Massachusetts