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Development and evaluation of methods.
Kennedy ER; Fischbach TJ; Song R; Eller PM; Shulma SA; Hull RD
NIOSH manual of analytical methods, fourth edition - third supplement. Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2003-154, 2003 Mar; :36-50
The development and evaluation of analytical methods that are useful, reliable and accurate for industrial hygiene monitoring problems require the application of some general guidelines and evaluation criteria. The guiding objective in this work requires that, over a specified concentration range, the method provide a result that differs no more than +/- 25% from the true value 95 times out of 100. The application of consistent evaluation criteria and guidelines is particularly important when methods are developed by different individuals and organizations (e.g., contractors or outside laboratories) and compiled into a single manual. Adherence to guidelines should minimize overlooking potential problems in the methodology during its development, as well as provide cohesiveness and uniformity to the method that is developed. This chapter provides an outline of a generalized set of evaluation criteria prepared by NIOSH researchers for the evaluation of sampling and analytical methodology .
Sampling-methods; Analytical-processes; Analytical-methods; Laboratory-equipment; Laboratory-techniques; Sample-preparation
NIOSH manual of analytical methods, fourth edition - third supplement
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division