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Mortality patterns among workers exposed to styrene in the reinforced plastic boatbuilding industry: an update.
Ruder AM; Ward EM; Dong M; Okun AH; Davis-King K
Am J Ind Med 2004 Feb; 45(2):165-176
BACKGROUND: Mortality was updated through 1998 for 5,204 workers exposed to styrene between 1959 and 1978 at two reinforced plastic boatbuilding plants. The a priori hypothesis: leukemia and lymphoma excesses would be found. METHODS: Standardized mortality ratios (SMR) and 95% confidence intervals (CI) used Washington State and U.S. rates. RESULTS: Overall, 860 deaths occurred (SMR 1.09, CI 1.02-1.17), with excess mortality for esophageal cancer (n = 12, SMR 2.30, CI 1.19-4.02), prostate cancer (n = 24, SMR 1.71, CI 1.09-2.54), and accidents (n = 99, SMR 1.26, CI 1.02-1.53). Among 2,062 highly exposed workers, urinary tract cancer (n = 6, SMR 3.44, CI 1.26-7.50) and respiratory disease (n = 12, SMR 2.54, CI 1.31-4.44) rates were elevated. Urinary tract cancer SMR increased with duration of employment. CONCLUSIONS: We found no excess leukemia or lymphoma mortality. Unanticipated excess urinary tract cancer and respiratory disease mortality, possibly associated with styrene exposure, are difficult to interpret and could be chance findings.
Boat-manufacturing-industry; Styrenes; Styrene-resins; Cancer; Cancer-rates; Mortality-rates; Mortality-data; Mortality-surveys; Statistical-analysis; Epidemiology; Blood-disorders; Respiratory-system-disorders; Pulmonary-system-disorders; Urogenital-system-disorders; Author Keywords: styrene; reinforced plastic industry; leukemia; cancer mortality; cohort mortality study; urinary tract cancer;
National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, Ohio 45226
Issue of Publication
American Journal of Industrial Medicine
Page last reviewed: October 16, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division