Permeation of of irritant mixtures through protective materials.
NIOSH 2004 Sep; :1-156
The hypothesis of the research was that permeation of specific irritative pesticides and metal working fluids (MWFs) through glove materials obeyed a published mathematical model that included mass percent composition, molar volume, and the octanol/water coefficient as independent variables. The solid pesticide wettable powder formulations investigated contained Captan, Folpet, Benomyl, Chlorothalonil, and Dichlorbenil as active ingredients. The liquid pesticide emulsifiable concentrates contained Propargite, Telone, and Telone/chloropicrin. There were also 5 different representative MWFs: Cool Flow SYN; Cool-Flow 1020; Cimperial 1020; Cimperial 1070; and Deolene D-4. The gloves examined included unsupported/unlined nitrile disposable (Safeskin and others) and chemically-resistant (Solvex) and when these did not prove appropriately resistant, laminates like Barrier and Silver Shield. The permeation technique utilized a shaker water bath at 30 degree C with a ASTM-type permeation cell, the I-PTC 600. The collection solution was analyzed by either gas chromatography-mass spectrometry (GC-MS), GC-electron capture detector (ECD). Damage to the glove material or surface residues were detected or quantified by reflectance Fourier transform infrared (FTIR) spectrophotometry. The permeation data revealed that the solid pesticides in water at their maximum field spraying concentrations permeated much more slowly than the undiluted liquid pesticide formulations so that wearing disposable nitrile gloves was sufficiently protective generally for protection from aqueous solutions containing pesticides to be sprayed. While Safeskin was not sufficiently protective for the propargite formulation, Solvex was. Both Safeskin and Solvex did not protect against Telone formulations, and Silver Shield proved to be the most protective laminate. Reflectance FTIR examination of the exposed dry glove materials allowed detection of pesticide residues. The quantitation of captan was achieved using a field-portable FTIR at a sensitivity that permitted ASTM breakthrough determinations. The permeation of MWFs through disposable nitrile gloves was unacceptable, and even Solvex nitrile suffered breakthrough for some MWFs after 8 hours of exposure. The modeling validation effort has still not been completed but should be within the next year for publication.
Protective-clothing; Protective-materials; Personal-protective-equipment; Gloves; Fungicides; Analytical-processes; Pesticides; Pesticides-and-agricultural-chemicals; Metalworking-fluids
Department of Environmental Health Sciences, School of Public Health, 650 Charles Young Jr. Drive South, Los Angeles, CA 90095-1772
133-06-2; 133-07-3; 17804-35-2; 1897-45-6; 1194-65-6; 76-06-2
Final Grant Report
National Institute for Occupational Safety and Health
University of California Los Angeles