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Evaluation of postural stability in workers exposed to lead at a secondary lead smelter.
Dick RB; Pinkerton LE; Krieg EF Jr.; Biagini RE; Deddens JA; Brightwell WS; Grubb PL; Taylor BT; Russo JM
Neurotoxicology 1999 Aug; 20(4):595-607
Postural sway testing was carried out on a group of 145 workers exposed to lead in a secondary lead smelter and 84 workers not exposed to lead in a hinge manufacturing plant. All workers were measured for blood lead levels (BLL) and erythrocyte zinc protoporphyrin (ZPP) concentrations at the time of testing and both a total cumulative and a time-weighted average BLL value was constructed for the lead exposed workers. The lead exposed workers mean BLL at the time of testing was 38.9 microg/dl and the non-exposed workers mean was 2.3 microg/dl. ZPP levels averaged 55.2 microg/dl for exposed workers and 18.9 microg/dl for non-exposed workers. Total cumulative BLL averaged 83476 microg/dl days for the exposed workers, with a mean time-weighted average BLL of 35.1 microg/dl. Six tests of postural stability, four two leg conditions and two single leg conditions were administered to all subjects using a force platform to produce measurements of sway for comparison purposes. The two leg conditions also manipulated the visual and proprioceptive systems. A statistically significant association was observed for sway measurements and the current BLL for all workers, but not with the current BLL of only the lead exposed workers. No statistically significant associations were present with the cumulative measures of long-term exposure. Of the six tests of sway, only the single leg conditions showed significant exposure effects. The results suggest effects of lead exposure among those with average BLL near 40.0 microg/dl, but only in the most challenging one leg conditions.
Posture; Lead production; Lead smelting; Lead compounds; Lead absorption; Lead poisoning; Blood samples; Blood tests; Visual fields; Visual perception; Statistical analysis; Author Keywords: Neurotoxicity; Postural Sway; Lead Exposure; Blood Lead; Zinc Protoporphyrin
Robert B. Dick, Ph., D, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, MS C-24, Cincinnati, Ohio 45226
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Page last reviewed: September 11, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division