Comparison of a convective mixing model's predictions to empirical results for aerosol dispersion in the human lung.
Ganser-G; McCawley-MA; Christie-I
Ann Occup Hyg, Inhaled Particles VIII 1997 Jan; 41(Suppl 1):571-575
Recent modeling work has attempted to use axial diffusion to explain the observed dispersion of an aerosol bolus in transit through the lung (Edwards, 1994). This type of modeling attempts to derive from first principles the underlying mechanism of aerosol dispersion. An alternative approach has used mixing theory derived from reactor vessels to surmount problems encountered in small-scale mixing (McCawley et al., 1988). Noting that Oltman (1985) had used an approach that is mathematically similar in applying network theory to this problem, it was decided to try to relate the number of vessels in series to the number of bifurcated generations in the lung.
Aerosol-particles; Aerosol-dispensers; Aerosol-sampling; Aerosols; Lung; Lung-function; Models
Annals of Occupational Hygiene, Inhaled Particles VIII