This supplement to the NIOSH Manual of Analytical Methods contains 39 new methods, acetoin (2558); alcohols combined (1405); aliphatic aldehydes (2018); aniline and o-toluidine in urine (8317); 1- and 2-bromopropane (1025); butoxyacetic acid in urine (8316); captan and thiophanate-methyl in handrinse (9202); captan and thiophanate-methyl on dermal patch (9205); cellulose insulation (7404); p-chlorobenzotrifluoride (1026); chromium, hexavalent by ion chromatography (7605); chromium, hexavalent, by field-portable spectrophotometry (7703); decabromodiphenyl oxide (2559); diacetyl (2557); 2-(dimethylamino)ethanol and 1-dimethylamino-2-propanol (2561); elements by icp (aqua regia ashing) (7301); elements by icp (hot block/hci/hno3 digestion) (7303); elements on wipes (9102); estrogenic compounds (5044); glycol ethers (2554); hydrogen cyanide (6017); isocyanates, total (map) (5525); isophorone (2556); isopropyl acetate (1460); ketones I (2555); ketones II (2553); lead in dust wipes (9105); maneb (dermal patch) (3600); maneb (hand wash) (3601); metalworking fluids (MWF) (5524); methyl acrylate (2552); methyl tin chlorides (5526); 1-nitropyrene in diesel particulates (2560); organic and inorganic gases by extractive FTIR (3800); 1,1,2,2-tetrachloroethane (2562); tetrakis(hydroxymethyl)phosphonium chloride (5046); thiophanate-methyl (5606); triazine herbicides and their metabolites in urine (8315); triphenyl tin chloride (5527); 18 revised methods, alcohols IV (1403); diesel particulate matter (as elemental carbon) (5040); elements by icp (nitric/perchloric acid ashing) (7300); esters 1 (1450); ethyl ether (1610); formaldehyde (2016); hippuric and methyl hippuric acids in urine (8301); hydrocarbons, aromatic (1501); hydrocarbons, BP 36-126 (1500); hydrocarbons, halogenated (1003); isopropyl ether (1618); lead by portable ultrasonic extraction/ASV (7701); methyl and ethyl methacrylate (2537); quartz in coal mine dust, by IR (7603); silica, crystalline, by XRD (7500); silica, amorphous (7501); silica, crystalline, by VIS (7601); silica, crystalline, by IR (7602); and seven new chapters. The method finder, table of contents, and indexes have also been updated to coincide with the changes. The replacement pages are included. The manual is a collection of air, biological, bioaerosol, and bulk analytical methods that NIOSH has evaluated. NMAM will be updated as methods are developed, evaluated or revised by NIOSH. These methods are intended to promote accuracy, sensitivity, and specificity in industrial hygiene analyses. The introduction states the purpose and use of the manual. Subsequent sections discuss the quality assurance, sampling, measurements, methods, standards, blanks, blind samples, recovery studies, duplicates, tracking, and reporting. In addition, information to be considered when sampling for airborne contaminants; types and uses of solid sorbents; factors affecting the collection of gases, vapors, and aerosols; sampling strategy and calibration techniques; and samplers is presented.