NIOSHTIC-2 Publications Search
Paternal occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and birthweight of offspring.
Lawson CC; Schnorr TM; Whelan EA; Deddens JA; Dankovic DA; Piacitelli LA; Sweeney MH; Connally LB
Dioxin 2003, 23rd International Symposium on Halogenated Environmental Organic Pollutants and POPs, August 24-29, 2003, Boston, Massachusetts. Boston, MA: RPJ Associates, 2003 Aug; 64:1-4
Agent Orange, a phenoxy herbicide, is a SO/50 mixture of the herbicides 2,4-D [(2,4-dichlorophenoxy)acetic acid] and 2,4,5-T [(2,4,5-trichlorophenoxy)acetic acid], which was contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). There have been few studies of paternal TCDD exposure and birthweight. The National Academy of Sciences (NAS) concluded there was insufficient or inadequate evidence to determine whether there is an association. We studied the pregnancy outcomes among wives of male workers highly exposed to chemicals contaminated with TCDD and among wives of non-exposed neighborhood referents that participated in a cross-sectional medical study. In the current paper we evaluate the association between paternal exposure to TCDD at the time of conception and birthweight of offspring.
Herbicides; Dioxins; Reproductive-hazards; Reproductive-effects; Epidemiology; Statistical-analysis
National Institute for Occupational Safety and Health, 4676 Columbia Pkwy, Cincinnati, OH 45226
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Dioxin 2003, 23rd International Symposium on Halogenated Environmental Organic Pollutants and POPs, August 24-29, 2003, Boston, Massachusetts
Page last reviewed: June 15, 2021
Content source: National Institute for Occupational Safety and Health Education and Information Division