Impact and extent of reproductive hazards in the workplace.
Birth Defects Res Part A Clin Mol Teratol 2003 May; 67(5):342
The task of effectively studying the many toxicants, physical agents, and biomechanical and psychosocial stressors which may constitute reproductive hazards in the workplace is daunting. While the main objective of researchers and clinicians is prevention of recognized adverse reproductive outcomes, there is growing recognition of a broad spectrum of chronic health outcomes potentially affected by reproductive hazards, including breast cancer. Clinicians providing care to exposed workers as well as researchers conducting human etiologic studies of reproductive hazards face significant barriers, including difficulties in the assessment of numerous and multiple exposures, and the intrinsic methodologic limitations of both animal studies and observational human studies, The National Institute for Occupational Safety and Health (NIOSH) has formed a National Occupational Research Agenda Team to encourage communication and partnering among reproductive toxicologists, clinicians, and epidemiologists. Several important team efforts will help interpret animal data and use large collections of population based information effectively. Results from these efforts will help researchers design epidemiologic studies which have the best prospects for interpretable results. NIOSH has used information from these efforts to improve the quality of exposure assessment in several current studies. Observational and experimental scientists and clinicians can partner to improve the quality of exposure assessment, thereby reducing limitations and increasing the quality of epidemiologic data.
Reproductive-hazards; Reproductive-effects; Teratogenesis; Teratology; Teratogens; Synergism; Education
Abstract; Conference/Symposia Proceedings
Birth Defects Research: Part A: Clinical and Molecular Teratology. 43rd Annual Meeting of the Teratology Society, 27th Annual Meeting of the Neurobehavioral Teratology Society, 22nd Annual Meeting of the Behavioral Teratology Society, 16th International Conference of the Organization of Teratology Information Services