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Ultrafine particles in the atmosphere.

Brown LM; Collings N; Harrison RM; Maynard AD; Maynard RL
Brown LM, Collings N, Harrison RM, Maynard AD, Maynard RL, eds. London: Imperial College Press, 2003 Aug; :1-320
The past decade has seen mounting evidence that atmospheric particles are more damaging to health than previously thought. Epidemiological studies relating population health to airborne particle concentrations provided some of the first indications of a hitherto unsuspected toxicity. There is a remarkable consistency of effect between different geographic locations, showing a correlation with the incidence of respiratory and cardiovascular diseases. Initially, these findings were received with some skepticism, because there appeared to be no plausible biological mechanism. However toxicological studies have since indicated a range of mechanisms that underpin the epidemiology, whereby airborne particles may damage human health. Many studies have now shown that some particles become more toxic per unit mass as their size decreases. Thus attention is focused upon particulate surface area or number per unit mass, rather than mass fraction, and one is led to consider 'ultrafine particles': those of effective diameter less than one-tenth of a micrometer. In March 2000 The Royal Society (London) hosted a multi-disciplinary discussion meeting to address issues surrounding ultrafine particles in the atmosphere. Eminent researchers from a wide range of disciplines met together over two days to consider the current state of our knowledge and understanding of ultrafine aerosol generation, characterization, transportation, exposure and toxicity. The result was a comprehensive overview of what we know, and what information is yet needed, about ultrafine particles and how they potentially impact our health. This collection of papers is based on the lectures given at the meeting, and likewise comprehensively documents the current state of affairs regarding ultrafine particles in the atmosphere. Chapters 1 to 3 consider the characterization of ultrafine particles. Chapters 4 to 8 follow on by considering the sources of ultrafine aerosols. The remaining chapters deal with the health effects associated with ultrafine particulate exposure: chapters 9 to 13 focus on the toxicology of ultrafines, while chapters 14 to 16 conclude by considering the epidemiology of ultrafine aerosol exposure. Sadly, Professor Glen Cass, author of chapter 2 on the chemical composition of atmospheric ultrafine particles, passed away prematurely in July 2001.
Particulates; Air-contamination; Toxic-effects; Respiratory-irritants; Respiratory-system-disorders; Cardiovascular-system-disorders; Biological-effects; Humans; Aerosol-particles; Aerosols; Nanotechnology
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Brown LM; Collings N; Harrison RM; Maynard AD; Maynard RL
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Research Tools and Approaches: Exposure Assessment Methods
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Ultrafine particles in the atmosphere.
Page last reviewed: October 26, 2020
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