A model for occupational epicondylitis.
NIOSH 2003 Mar; :1-22
Tendinosis is not well understood. It is a painful, degenerative process with features that include high fibroblast density, increased number of blood vessels, and disorganization of the collagen matrix (Kraushaar, 1999). Elbow tendinosis is a repetitive motion injury and is found in sports (Field, 1998) and workplaces requiring manual handling and repetitive, forceful work (e.g., the construction industry, Silverstein, 1998). The research plan for this project involves modifying a repetitive finger loading rabbit model to investigate epicondylitis. This research will: (1) develop and validate the model, (2) identify relationships between the severity and location of the biochemical and histologic outcome measures, and (3) determine exposure-response relationships of force and repetition on the biologically important histologic and biochemical outcome measures. The results will provide a foundation to examine the relative importance of force, repetition, recovery, and duration in the pathogenesis of work-related epicondylitis.
Musculoskeletal-system-disorders; Ergonomics; Repetitive-work; In-vivo-study; Proteins; Analytical-models; Biomechanics; Force; Exposure-levels; Occupational-medicine
University of California-San Francisco, Department of Medicine, Division of Occupational Medicine, Ergonomics Program, 1301 South 46th St., Building 163, Richmond, CA, 94804
Final Grant Report
Disease and Injury; Musculoskeletal Disorders of the Upper Extremities
National Institute for Occupational Safety and Health
University of California-San Francisco, Department of Medicine, Division of Occupational Medicine, Ergonomics Program, Richmond, CA, 94804