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Priorities for development of research methods in occupational cancer.
Ward EM; Schulte PA; Bayard S; Blair A; Brandt-Rauf P; Butler MA; Dankovic D; Hubbs AF; Jones C; Karstadt M; Kedderis GL; Melnick R; Redlich CA; Rothman N; Savage RE; Sprinker M; Toraason M; Weston A
Environ Health Perspect 2003 Jan; 111(1):1-12
Occupational cancer research methods was identified in 1996 as 1 of 21 priority research areas in the National Occupational Research Agenda (NORA). To implement NORA, teams of experts from various sectors were formed and given the charge to further define research needs and develop strategies to enhance or augment research in each priority area. This article is a product of that process. Focus on occupational cancer research methods is important both because occupational factors play a significant role in a number of cancers, resulting in significant morbidity and mortality, and also because occupational cohorts (because of higher exposure levels) often provide unique opportunities to evaluate health effects of environmental toxicants and understand the carcinogenic process in humans. Despite an explosion of new methods for cancer research in general, these have not been widely applied to occupational cancer research. In this article we identify needs and gaps in occupational cancer research methods in four broad areas: identification of occupational carcinogens, design of epidemiologic studies, risk assessment, and primary and secondary prevention. Progress in occupational cancer will require interdisciplinary research involving epidemiologists, industrial hygienists, toxicologists, and molecular biologists.
Occupational diseases; Cancer; Cancer rates; Morbidity rates; Mortality rates; Mortality data; Environmental exposure; Carcinogenesis; Carcinogens; Risk factors; Industrial hygienists; Epidemiology; Molecular biology; Author Keywords: cancer research; National Occupational Research Agenda; occupational health; research priorities
P.A. Schulte, NIOSH, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
Issue of Publication
DSHEFS; EID; DART; HELD
Disease and Injury: Asthma and Chronic Obstructive Pulmonary Disease; NORA Implementation
Environmental Health Perspectives
OH; MD; NY; VA; DC; NC; CT
Page last reviewed: March 3, 2021
Content source: National Institute for Occupational Safety and Health Education and Information Division