Influence of early COPD on employment status.
Harber-P; Tashkin-DP; Hnizdo-E; Simmons-M
Am J Respir Crit Care Med 2003 Apr; 167(7):A240
There is limited information about the impact of early COPD on employment status. Participants in a longitudinal smoking cessation intervention trial were followed 6 years. All had early COPD (defined as 55 < FEV1 < 90% predicted with FEV1/FVC ratio < = 0.70). Employment status and spirometry were determined at baseline and at 5 annual follow-up examinations. Airway responsiveness (FEV1 methacholine dose slope) was measured twice. At each visit, subjects were asked employment status, dust exposure, fume exposure, and mask use. Influence of these factors upon employment status at the 5th annual follow-up was determined with a series of logistic regression analyses. The following predictors of continued employment at the 5th annual follow up were considered: baseline FEV1 residual, baseline FEV1/FVC, airway responsiveness, change in FEV1 between baseline and year 5, age, gender, exposures (dust, fume, mask use), "ever exposed" to occupational agents, and years in current job. Overall, age was consistently a significant negative predictor of remaining at work after 5 years. Neither mild abnormality of spirometry nor FEV1-exposure interactions were predictive. Similarly, methacholine reactivity did not affect employment at years. "Ever exposed" (men, OR= 0.73) and years in current! job women, OR = 0.97) were inversely related to likelihood of employment at five years. Early COPD does not lead to change in employment status. However, this does not exclude possibility that subtle effects of accelerated FEV1 decline or airway hyperresponsiveness on employment occur early in the career of individuals.
Spirometry; Smoking; Air-sampling; Airborne-dusts; Airborne-particles; Dust-exposure; Dust-particles; Dusts; Fumes; Occupational-exposure; Particulate-dust; Particulates; Respiratory-system-disorders; Pulmonary-system-disorders; Bronchial-asthma; Surveillance
Abstract; Conference/Symposia Proceedings
Disease and Injury: Asthma and Chronic Obstructive Pulmonary Disease; Construction
American Journal of Respiratory and Critical Care Medicine, 2003 International Conference, The American Thoracic Society, Seattle, WA, May 16-21, 2003