Home enviroment and childhood asthma in a rural Iowa county.
Svendsen-ER; Reynolds-SJ; Merchant-JA; Naleway-AL; Stomquist-AM; Thorne-PS
Am J Respir Crit Care Med 2002 Apr; 165(8)(Suppl):A489
Childhood asthma is epidemic throughout the industrialized world. Most literature reports lower asthma and allergy prevalence rates among rural and agricultural populations. In Round I of the Keokuk County Rural Health Study (KCRHS) (a rural longitudinal cohort study), a relatively high rate of childhood asthma prevalence was found: 16.3 %. Further study was warranted to explain the high prevalence. A nested case-control study was performed within Round II of the KCRHS. Extensive home environmental assessments were performed, in addition to enhanced clinical evaluations. In univariate analysis, allergy and sensitization (especially to farm, grass, and mold antigens), increasing exposure to mold/water damage, and always used wood to heat were significantly associated with asthma prevalence. Atopy (OR: 3.73, 95% CI: 1.21-11.42) and mildew/water damage exposure (OR: 2.45, 95%CI: 1.20-5.00) were significantly associated with asthma prevalence even after adjusting for male gender, severe chest illness prior to 2 years of age, and high-risk birth in a multiple logistic regression. Increasing farm and mold exposures were significantly associated with increased asthma prevalence, independent of gender, early severe chest illnesses, and neo-natal risk factors. This abstract does not necessarily represent EPA policy.
Children; Respiratory-system-disorders; Respiratory-irritants; Pulmonary-system-disorders; Pulmonary-function; Pulmonary-disorders; Allergies; Allergic-reactions; Long-term-study; Sensitization; Molds; Agriculture
Abstract; Conference/Symposia Proceedings
Cooperative Agreement; Grant
American Journal of Respiratory and Critical Care Medicine, 2002 International Conference, The American Thoracic Society, Atlanta Georgia, May 17-22, 2002
University of Iowa, Iowa City, Iowa