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Interaction between noise and asphyxiants: a concern for toxicology and occupational health.
Toxicol Sci 2002 Mar; 66(1):1-3
Occupational health, in its mission to identify and prevent work-related disorders, often relies on finding from toxicological studies. Many occupational issues, such as the exposure parameters and the mechanisms responsible for causing disorders, can only be addressed through toxicological experiments. In particular, more biological and toxicological research is needed to understand the toxicity of mixtures and the interaction between mixture components. Human data are characterized by great individual variability that arises mainly from differences in medical and exposure histories and in susceptibility. This variability makes it challenging to separate the effects of each agent, and to determine with precision the kind of interaction between agents.
Occupational-health; Workers; Work-environment; Injuries; Workplace-studies; Occupational-health; Toxicology; Noise-induced-hearing-loss; Hearing-loss; Ototoxicity; Auditory-system
Thais C. Morata, Hearing Loss Prevention Section, Division of Applied Research and Technology, National Institute for Occupational Safety and Health, C27, 4676 Columbia Parkway, Cincinnati, Ohio 45226, USA
Issue of Publication
Disease and Injury: Hearing Loss
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division