A sampling and analysis method for two amino alcohols.
American Industrial Hygiene Conference and Exposition, June 1-6, 2002, San Diego, California. Fairfax, VA: American Industrial Hygiene Association, 2002 Jun; :86
During a recent NIOSH field survey, thermal desorption tubes were used to qualitatively determine any volatile organic compounds to which the workers were being exposed. Two major compounds in the samples were identified by gas chromatography-mass spectrometry as N,N-dimethylethanolamine (DMEA) and N,N-dimethylisopropanolamine (DMIPA). A short-term method development was con- ducted to quantify full-shift concentrations of these compounds, potentially at fairly high levels. A desorption study was conducted using various solid sorbents-silica gel, carbon molecular sieve, and XAD resins. Methanol was used as the desorbing solvent. Only the XAD resins gave desorption efficiencies above the NIOSH criteria of 75% at various levels. Further study showed only the XAD- 7 sorbent efficiently trapped these particular amines. The gas chromatography-flame ionization (GC- FID) method used a dimethylpolysiloxane bonded phase capillary column. The limits of detection (LOD) and quantitation (LOQ) for both amines were approximately 4 ug and 10 ug per sample respectively. Calibration curves were linear over a range of 4 ug to 550 ug per sample. Additional studies were conducted to check the storage stability of spiked samples, showing that samples were stable for at least three weeks when stored cold (- 4 C). The method was successfully used in a field study for the analysis of over 200 personal samples. The method will be published in the next supplement of the NIOSH Manual of Analytical Methods (NMAM).
Sampling-methods; Analytical-methods; Amino-compounds; Organic-compounds; Exposure-levels; Gas-chromatography; Mass-spectrometry; Workers
American Industrial Hygiene Conference and Exposition, June 1-6, 2002, San Diego, California