Computer controlled ozone inhalation exposure system.
McKinney-W; Goldsmith-T; Frazer-D
Biomedical engineering recent developments: proceedings of the Twenty First Southern Biomedical Engineering Conference, September 28 - 29, 2002, Bethesda, Maryland. Vossoughi J, ed. Washington, DC: Medical and Engineering Publishers, Inc., 2002 Sep; :319-320
Systems used to expose laboratory animals to various gases and aerosols are an important aspect of inhalation toxicology studies. These systems are crucial in controlling the dose of toxicant the animals receive. The object of this project was to develop a computer controlled ozone inhalation exposure system for the evaluation of health risks associated with ozone. The system is capable of a wide range of exposure concentrations (0.1 to 8.0 PPM) and can be used for various exposure times (1-8 hrs). Ozone concentration steady-state error was less than one percent when closed-loop control principles were applied. Additionally, when compared with the open loop response rise time, the step response time was cut in half after closed loop control was implemented.
Toxicology; Air-flow; Air-sampling-techniques; Laboratory-animals; Laboratory-equipment; Exposure-chambers; Exposure-methods; Inhalation-studies
Biomedical engineering recent developments: proceedings of the Twenty First Southern Biomedical Engineering Conference, September 28 - 29, 2002, Bethesda, Maryland