Nonlinear model for offline correction of pulmonary waveform generators.
Reynolds-JS; Stemple-KJ; Petsko-RA; Ebeling-TR; Frazer-DG
IEEE Trans Biomed Eng 2002 Dec; 49(12)(Pt 2):1567-1573
Pulmonary waveform generators consisting of motor-driven piston pumps are frequently used to test respiratory-function equipment such as spirometers and peak expiratory flow (PEF) meters. Gas compression within these generators can produce significant distortion of the output flow-time profile. A nonlinear model of the generator was developed along with a method to compensate for gas compression when testing pulmonary function equipment. The model and correction procedure were tested on an Assess Full Range PEF meter and a Micro DiaryCard PEF meter. The tests were performed using the 26 American Thoracic Society standard flow-time waveforms as the target flow profiles. Without correction, the pump loaded with the higher resistance Assess meter resulted in ten waveforms having a mean square error (MSE) higher than 0.001 L2/s2. Correction of the pump for these ten waveforms resulted in a mean decrease in MSE of 87.0%. When loaded with the Micro DiaryCard meter, the uncorrected pump outputs included six waveforms with MSE higher than 0.001 L2/s2. Pump corrections for these six waveforms resulted in a mean decrease in MSE of 58.4%.
Models; Mathematical-models; Respiratory-function-tests; Respiratory-equipment; Pulmonary-function; Pulmonary-function-tests
Engineering and Controls Technology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505
Disease and Injury: Asthma and Chronic Obstructive Pulmonary Disease
IEEE Transactions on Biomedical Engineering