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Nonlinear model for offline correction of pulmonary waveform generators.

Reynolds JS; Stemple KJ; Petsko RA; Ebeling TR; Frazer DG

IEEE Trans Biomed Eng 2002 Dec; 49(12)(Pt 2):1567-1573

https://doi.org/10.1109/TBME.2002.805484

20022351

Pulmonary waveform generators consisting of motor-driven piston pumps are frequently used to test respiratory-function equipment such as spirometers and peak expiratory flow (PEF) meters. Gas compression within these generators can produce significant distortion of the output flow-time profile. A nonlinear model of the generator was developed along with a method to compensate for gas compression when testing pulmonary function equipment. The model and correction procedure were tested on an Assess Full Range PEF meter and a Micro DiaryCard PEF meter. The tests were performed using the 26 American Thoracic Society standard flow-time waveforms as the target flow profiles. Without correction, the pump loaded with the higher resistance Assess meter resulted in ten waveforms having a mean square error (MSE) higher than 0.001 L2/s2. Correction of the pump for these ten waveforms resulted in a mean decrease in MSE of 87.0%. When loaded with the Micro DiaryCard meter, the uncorrected pump outputs included six waveforms with MSE higher than 0.001 L2/s2. Pump corrections for these six waveforms resulted in a mean decrease in MSE of 58.4%.

Models; Mathematical-models; Respiratory-function-tests; Respiratory-equipment; Pulmonary-function; Pulmonary-function-tests Author keywords: American Thoracic Society; gas compression, nonlinear; pump; waveform generator; Author Keywords: American Thoracic Society; ATS; gas compression; nonlinear, pump, waveform generator

Engineering and Controls Technology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505

IEBEAX

20021201

Journal Article

JReynolds@cdc.gov

2003

12

0018-9294

HELD; DRDS

Disease and Injury: Asthma and Chronic Obstructive Pulmonary Disease

IEEE Transactions on Biomedical Engineering

WV