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Effects of vibration on vascular permeability in rats.
Cezeaux JL; Lindsey WG; Wiseman L
Biomedical engineering recent developments: proceedings of the Twenty First Southern Biomedical Engineering Conference, September 28 - 29, 2002, Bethesda, Maryland. Vossoughi J, ed. Washington, DC: Medical and Engineering Publishers, Inc., 2002 Sep; :213-214
Evidence suggests that damage due to vibration exposure may be related to alterations in capilliary permeability. The aim of this study was to investigate the effect of vibration exposure on vascular permeability. Rats were exposed to whole-body vibration at 125 Hz and 50 mls2 rms for 4 hours/day for 5 days. Vascular permeability in the gastrocnemius muscle and the liver was evaluated via Evans blue dye uptake. Results indicate that the uptake in the liver was 110% higher in vibrated inimals compared to controls while that in the gastrocnemius was 38% higher, indicating that vibration exposure at the parameters studied leads to increases in vascular permeability.
Cardiovascular-system-disorders; Vibration-disease; Circulatory-system; Nerve-damage; Neurovascular-disorders; Animal-studies; In-vitro-studies; In-vivo-studies; Musculoskeletal-system; Tools; Nervous-system; Hand-tools
Disease and Injury: Musculoskeletal Disorders of the Upper Extremities; Research Tools and Approaches: Control Technology and Personal Protective Equipment
Biomedical engineering recent developments: proceedings of the Twenty First Southern Biomedical Engineering Conference, September 28 - 29, 2002, Bethesda, Maryland
Page last reviewed: July 30, 2021
Content source: National Institute for Occupational Safety and Health Education and Information Division