Involvement of Sphingomyelinase in Insulin-induced Phosphatidylinositol 3-kinase Activation.
Huang-C; Ma-WY; Ding-M; Li-J; Shi-X; Castranova-V; Vallyathan-V; Bode-AM; Dong-Z
FASEB J 2001 Apr; 15(6):1113-1114
SPECIFIC AIM- This manuscript aims to elucidate the mechanism by which insulin activates phosphatidylinositol 3-kinase (PI-3 kinase), especially the role of sphingomyelinase (SMase) in insulin-induced PI-3 kinase activation.
Animal-studies; Laboratory-testing; Laboratory-animals; Proteins; Phosphates; Cell-growth
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