A system for analyzing aerosols produced by humans during respiratory maneuvers.
Goldsmith-T; Afshari-A; Azadi-S; Jones-B; Frazer-D
Ann Biomed Eng 2001 Oct; 29(Suppl 1):S-141
It has long been known that the spread of aerosols from person to person is one of the leading causes of respiratory disease. In order to characterize aerosols produced by humans, a system was constructed which measured the number and size of aerosols produced during voluntary coughs and forced exhalations (FE). The measurement system was enclosed in a chamber and maintained at 37 degrees C to minimize alterations in aerosol characteristics due to condensation-evaporation. Air expired through a disposable mouthpiece entered a spirometer which measured the flow and volume of the maneuver. A particle analyzer, used to characterize the aerosols, pulled air from the spirometer. Aerosol size distributions between 0.3-20 um were determined using an optical particle counter. Custom software was developed which acquired the data and ensured the validity of the maneuver in real-time. In order to evaluate the system, volunteer subjects performed coughs and FE's after breathing HEPA filtered air. Characteristics of aerosols produced during coughs and FE's produced similar size distributions in terms of counts and mass. Results indicate a mass mode appeared at 6 um. This project is supported in part by FAA IAG 97-11.
Aerosols; Aerosol-sampling; Respiratory-system-disorders; Aerosol-particles; Respiratory-infections; Humans; Diseases; Infectious-diseases; Disease-transmission; Disease-vectors
Abstract; Conference/Symposia Proceedings
Annals of Biomedical Enginerring