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Criteria for a recommended standard... occupational exposure to glycidyl ethers.
Rockville, MD: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 78-166, 1978 Jun; :1-197
Glycidyl ethers are characterized by the presence of a three-carbon chain with an epoxide group and an ether linkage. This recommended standard applies to monoglycidyl ethers and diglycidyl ethers that contain an alkyl group, an aromatic group, or a moiety of the structure -(RO)n-R'. It does not include any halogenated compounds or polymerized forms. Most of the glycidyl ethers are liquids but some are solids. The most common use of these compounds is as reactive diluents in epoxy resins. Toxicologic data concerning these compounds are scarce, but those available show that glycidyl ethers are primary skin and eye irritants and that they are potential skin sensitizing agents. Some data suggest that di(2,3-epoxypropyl) ether should be regarded as a potential occupational carcinogen and that n-butyl glycidyl ether is a mammalian mutagen. Some glycidyl ethers have also produced cytotoxic effects in animals.
Hazardous-materials; Industrial-medicine; Exposure-levels; Standards; Industrial-hygiene; Thresholds; Occupational-safety; Air-sampling; Maximum-permissible-concentrations; Mutagenesis; Teratogenesis; NIOSH-Criteria-Document
106-92-3; 4016-14-2; 122-60-1; 2426-08-6; 2238-07-5
Numbered Publication; Criteria Document
NTIS Accession No.
DHEW (NIOSH) Publication No. 78-166; Contract-099-74-0031
National Institute for Occupational Safety and Health
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division