The U.S. Bureau of Mines investigated the Sheep Creek prospect in the north-central Alaska range to evaluate the pb, zn, ag, and sn resources. The studies included field investigations, mineralogical characterization, and concentration tests. Mineralization at Sheep Creek consists of disseminated, banded, and massive pyrite, sphalerite, and galena. Tin occurs as grains of cassiterite (sNO2) in the quartz-mica matrix and within pyrite and sphalerite grains, and ag occurs in solid solution within the galena. Three bulk surface samples and two sets of core samples were collected at the Sheep Creek prospect for this study. Gravity concentration yielded products with up to 30 pct sn, and the best result was a product that recovered 52 pct of the sn at a grade of 22 pct sn. Bulk sulfide flotation yielded products that recovered up to 89 pct of the zn, 73 pct of the pb, and 75 pct of the ag, but grades were relatively low; selective flotation would significantly increase the grades.