As part of research conducted in its mission to effect pollution abatement, the Bureau of Mines, U.S. Department of the Interior, is developing a dewatering technique that allows for disposal of phosphatic clay wastes, for reuse of water now lost with clays, and for reclamation of mined land. The technique utilizes a high- molecular-weight nonionic polyethylene oxide polymer (peo) that has the ability to flocculate and dewater phosphatic clay wastes. A synergistic flocculation study was made to determine whether a portion of peo could be replaced by other reagents. Several groups of reagents were tested: (1) those that increased the zeta potential of the phosphatic clay wastes; (2) those capable of hydrogen bonding; and (3) those which flocculated the phosphatic clay waste. Reduction in peo consumption occurred only with addition of those reagents able to flocculate the slime. The use of natural guar gums resulted in a lower peo requirement and also yielded a dewatered product of higher solids content, 43 to 45 percent, versus 33 to 35 percent obtained with peo alone.