This report describes mineral investigations conducted by the Bureau of Mines during the 1985 and 1986 field seasons in the Southern Chilkat Range of northern southeast Alaska. These investigations were part of the Bureau's study of mineral resources in the Juneau Mining District. Field investigations included geologic mapping and sampling of known mines, prospects, and mineral occurrences in the study area. In addition, selected areas favorable for hosting mineral deposits were examined using geologic reconnaissance, geochemical sampling, and ground geophysics. During fieldwork, 179 geochemical samples were collected from 116 different locations. Analytical results of these samples defined polymetallic geochemical anomalies throughout the study area. Additionally, precious metal anomalies are broadly distributed in volcanic and clastic rocks, along with quartz veins, areawide. An area of special interest contains gold and base metal mineralization in interlayered volcanic and clastic rocks. This mineralized area crops out in mountainous terrain 3 miles to the west of Sullivan Island. All of the old mines in the area have moderate mineral development potential owing to their various grades of mineralization. The widespread occurrence of geochemical anomalies combined with favorable geology for volcanic and sediment hosted mineralization suggests the study area is favorable for economic mineral occurrences.