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Byssinosis and other textile dust-related lung diseases.

Schachter EN

Textbook of clinical occupational and environmental medicine. Rosenstock L, Cullen MR, eds. Philadelphia, PA: W.B. Saunders Company, 1994 Jul; :209-224

00238251

This review discussed various aspects of byssinosis and other lung diseases caused by exposure to dust in the textiles industry. Epidemiological studies have linked cotton dust exposure to byssinosis in the textile industry and have resulted in some of the most stringent environmental standards ever developed in the work in an attempt to control the spread of this disease. A great deal has been learned about the pathogenesis of byssinosis. The release of pharmacologic mediators either preformed such as histamine or serotonin, or synthesized de-novo such as leukotrienes, has been proposed to explain the mechanism of the acute changes seen with exposure to cotton dust. Immunologic mechanisms have been proposed to explain clinical findings in byssinosis. At least 50 biologically active components of cotton dust exist that could contribute to pathologic reactions, including endotoxin and tannins. Clinical features of textile worker's disease were discussed and the clinical course of acute versus chronic disease was delineated. Diagnostic steps included history taking, lung function studies, physical examination, laboratory evaluation, challenge testing, immunologic testing and other tests. Treatment and prevention, compensation, surveillance and dust control were discussed as well.

NIOSH-Grant; Pulmonary-system-disorders; Pulmonary-function-tests; Lung-function; Breathing; Dust-exposure; Dust-inhalation; Cotton-dust; Plant-dusts; Occupational-respiratory-disease; Textile-workers; Textiles-industry

Medicine Mount Sinai Medical Center One Gustave L Levy Place New York, N Y 10029

19940701

Chapter

Rosenstock L; Cullen MR

709316

Grant

1994

9780721634821

Grant-Number-R01-OH-02593

Textbook of clinical occupational and environmental medicine

NY

Mount Sinai School of Medicine, New York, New York