A Dichotomous Sampler for TRIG Aerosol and Vapor.
Rando-RJ; Lefante-JJ; Poovey-HG
Section of Environmental Medicine, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana 1995 Jun:51 pages
An analytical technique was developed to reliably measure total reactive isocyanate group (TRIG) in workplace atmosphere samples and the technique was adapted for use in a dichotomous sampler that would separately collect and measure TRIG in the vapor and condensed phases. Three candidate derivatizing agents for TRIG measurement were evaluated: methoxy-phenylpiperazine (MOPIP), 9-methylamino- methylanthracene (MAMA), and tryptamine (TRYP). Six commercial formulations of isocyanate oligomers/polyurethane prepolymers were assayed by derivation with MAMA followed by high performance liquid chromatography with ultraviolet absorbance and fluorescence detection. A dichotomous sampler consisting of an impactor inlet in series with two sections of annular denuder tube followed by a backup filter was used to study the partitioning of 4,4'- diphenylmethane-diisocyanate (101688) between the vapor phase and condensed phase in an atmosphere of condensation aerosol ranging from 24 to 335 micrograms/cubic meter. Test atmospheres of HDI vapor and of 1,6-hexamethylenediisocyanate (822060) 1,6- hexamethylenediisocyanate-biuret (4035896) aerosols were generated and sampled with the dichotomous sampler using MAMA reagent. The dichotomous sampler was used to measure vapor and condensed phase TRIG in workplace atmospheres.
NIOSH-Grant; Grants-other; Air-quality-monitoring; Air-sampling-techniques; Isocyanates; Plastics-industry; Industrial-hygiene;
Medicine Tulane University 1700 Perdido St New Orleans, LA 70112
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Other Occupational Concerns; Grants-other;
Section of Environmental Medicine, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana
Tulane University of Louisiana, New Orleans, Louisiana