Analysis of complex mixtures of vapors in ambient air by fast-gas chromatography.
Ke-H; Levine-SP; Berkely-R
J Air Waste Manage Assoc 1992 Nov; 42(11):1446-1452
Fast gas chromatography (GC) as a method of separating and analyzing complex mixtures of organic vapors in ambient air was evaluated. Fast GC was based on using optimized components for each module in the GC system. The injector utilized a gas cooled and electrically heated capillary metal trap for focusing and reinjecting the sample as an extremely narrow band at the top of the column. Rapid heating was achieved by a capacitive discharge system which could increase the trap temperature by as much as 300 degrees-C in less than 20 milliseconds. The heart of the system was an HNU Systems model 301 gas chromatograph fitted with a flame ionization detector (FID) or electron capture detector (ECD). The stationary phase consisted of 5, 10, or 30 meter (m), 0.25 millimeter inside diameter capillary columns filled with 0.1 micrometer bonded methyl-silicone. Hydrogen was used as the carrier gas with the FID, and hydrogen or argon containing 5% methane was the carrier gas used with the ECD. The separations were done isothermally at temperatures of 40 to 100 degrees. Frozen samples consisting of mixtures containing up to 34 components could be separated and analyzed within 8 to 100 seconds. Separations equivalent to 950 effective theoretical plates per second of analysis time (TP/sec) could be obtained when the FID was used and separations of up to 300TP/sec could be achieved with the ECD. The authors conclude that fast GC can be applied successfully to separating complex mixtures of organic vapors using FID and ECD systems.
NIOSH-Publication; NIOSH-Grant; Grants-other; Organic-vapors; Analytical-methods; Gas-chromatography; Laboratory-equipment; Organic-compounds; Chromatographic-analysis
Environmental & Indust Health School of Public Health II 1420 Washington Heights Ann Arbor, MI 48109-2029
Journal of the Air and Waste Management Association
University of Michigan at Ann Arbor, Ann Arbor, Michigan