The responsibilities of the various agencies in the United States in the management of occupational exposure limits were described. Establishing new and revising current regulations takes place through a scheme developed by the Department of Labor, with both OSHA and the Mine Safety and Health Administration (MSHA) involved. Several agencies may make recommendations including NIOSH, the Environmental Protection Agency, and others. An Advance Notice of Proposed Rulemaking appears in the Federal Register, allowing time for written responses from parties interested in the topic over a 30 to 90 day period. The Department of Labor reviews and examines the information made available and then publishes a Notice of Proposed Rulemaking in the Federal Register, inviting written comments, testimony, and new data to be submitted to the docket. An Informal Public Hearing is held. NIOSH offers formal recommendations including Criteria Documents, Current Intelligence Bulletins, Alerts, written testimony, and miscellaneous documents. The process used to prepare Criteria Documents was described. Nominations for consideration are made to a priority review committee which examines the requests and places then in decreasing order of importance according to the following list: frequency of use, extent of exposure and background exposures, numbers of workers exposed, severity and type of adverse health effects, technical feasibility of controls, availability of sampling and analytical methods, quality of available data, substitution, interactions (synergistic or multiplicative), existing standards, and other considerations. The elements of the Criteria Document were noted and briefly described.