Risk of lung cancer among former chromium smelter workers.
Am J Ind Med 1996 May; 29(5):491-500
The risk of lung cancer among former chromium (7440473) smelter workers was determined. The cohort was composed of 3,408 workers from four former chromate producing facilities in northern New Jersey; subjects worked at the facilities at some time between 1937 and 1971. The study group was categorized by race, facility, duration, and latency. Proportionate mortality and proportionate cancer mortality ratios (PCMR) were calculated for the facilities both together and individually. Lung cancer was the cause of 12.9% of the deaths in this study. The overall risk for lung cancer was a PCMR of 1.51 for white men and 1.34 for black men; risk increased with increasing duration of employment and latency since time of first employment. The PCMR for nasal cavity and/or sinus cancer was also significantly increased among white workers. Former chromium workers remained at significantly increased risk of lung cancer despite cessation of exposure. Specific exposure data and information on smoking habits were not available. The authors conclude that the observed trends with duration and latency are supportive of a causal relationship between work in these facilities and the development of lung cancer as well as nasal cavity and/or sinus cancer; these findings emphasize the need for developing early detection tests for lung cancer.
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Lung-cancer; Risk-analysis; Worker-health; Cancer-rates; Chromium-compounds; Occupational-exposure; Mortality-data; Industrial-hazards
Occupation & Environ Hlth Ser New Jersey St Dept of Hlth CN 360 Trenton, N J 08625
American Journal of Industrial Medicine
New Jersey State Dept of Health, Trenton, New Jersey