Guidelines for air sampling and analytical method development and evaluation.
Kennedy ER; Fischbach TJ; Song R; Eller PM; Shulman SA
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 95-117, 1995 May; :1-110
The protocol for evaluation of sampling and analytical methods for airborne contaminants originally developed in 1974 for NIOSH and OSHA was expanded; these guidelines provided the expanded protocol. Procedures to follow in estimating the precision, bias and accuracy of a sampling and analytical method were presented. Guidance and procedures to evaluate a method relative to the 25% accuracy criterion in terms of one of three mutually exclusive possible conclusions (positive, negative, or inconclusive) were included. The procedure was made up of five steps: selection of compounds for method development and evaluation; development of the sampling and analytical method; evaluation of the method; preparation of a written version of the method; and preparation of a technical report on the development and evaluation. The method evaluation section discussed recovery of the analyte from the medium, stability of analyte on the sampling medium, stability of the sampling medium prior to use, sample generation, capacity of the sampler and the sampling rate, pressure drop across the sampler, precision, bias, and accuracy, and field evaluation.
NIOSH-Author; Sampling-equipment; Sampling-methods; Samplers; Air-samplers; Air-quality-monitoring; Analytical-methods
NTIS Accession No.
DHHS (NIOSH) Publication No. 95-117
National Institute for Occupational Safety and Health