Differentiation of the ILO boundary chest roentgenograph (0/1 to 1/0) in asbestosis by high-resolution computed tomography scan, alveolitis, and respiratory impairment.
Harkin-TJ; McGuinness-G; Goldring-R; Cohen-H; Parker-JE; Crane-M; Naidich-DP; Rom-WN
J Occup Environ Med 1996 Jan; 38(1):46-52
The 1980 International Labor Organization (ILO) International Classification of the Radiographs of the Pneumoconioses for asbestosis was compared with high resolution computed tomography (HRCT) scan in 37 subjects occupationally exposed to asbestos (1332214) for at least 5 years. A grid system was used for scoring fibrotic pleural and parenchymal changes on HRCT. Bronchoalveolar lavage (BAL) was used to assess alveolitis and pulmonary function testing was used to evaluate respiratory impairment in the subjects. Most of the subjects had chest radiographs near the 0/1 to 1/0 boundary. There were 26 subjects with a normal HRCT parenchymal grid score, and 11 subjects with an abnormal HRCT grid score. The ILO classification categorized 28 subjects as normal and nine as abnormal. The HRCT and ILO methods were concordant for 23 identified as normal and six identified as abnormal. Subjects identified as normal by HRCT also had normal pulmonary physiology, and BAL results. HRCT and ILO results concordant for abnormality were found to be associated with a reduced ratio of reduced forced expiratory volume in 1 second to forced vital capacity, reduced diffusing capacity, and alveolitis. The authors conclude that the HRCT grid scores and the ILO classification were excellent methods for the assessment of asbestosis.
NIOSH-Publication; NIOSH-Author; NIOSH-Cooperative-Agreement; Respiratory-system-disorders; Pneumoconiosis; Chest-X-rays; Diagnostic-techniques; Pulmonary-function-tests; Humans
Journal of Occupational and Environmental Medicine